Genomic surveillance is ongoing so that scientists can determine whether the combination of mutations in C.1.2 makes it more transmissible than other variants.īecause there has been a steady increase in the number of C.1.2 genomes in South Africa, the researchers will further investigate the impact of the effectiveness of the Covid vaccines against this variant in the lab. This antibody is triggered by natural infection or vaccination. Of greater concern, however, is that C.1.2 has accumulated additional mutations, which are also likely to impact how well neutralising antibodies, a critical part of the body’s immune response to a virus, respond to the variant. In other words, it promotes the transmission of the virus in people. These changes have also been seen in other VOC, including Beta which dominated SA’s second wave, and are known for having increased infectivity through its ability to replicate. The newly emerged sequences they studied contained multiple changes within the virus's spike protein (how the virus enters human cells). The recent analysis is the “work of dozens of scientists as part of the Network of Genomic Surveillance in South Africa (NGS-SA)”, co-author, Professor Tulio de Oliveira and director of KRISP (Kwazulu-Natal Research Innovation and Sequencing Platform), said in a tweet.Īccording to their paper, C.1.2 is highly mutated compared to C.1, as well as the other VOC and VOI identified to date. The process of genomic sequencing allows scientists to monitor how the virus changes over time into new variants. The SARS-CoV-2 virus is closely monitored through South Africa’s network of genomic surveillance. These sequences were distinct from C.1.1, which is why the researchers assigned them to the PANGO lineage C.1.2 on 22 July 2021. It was then assigned to PANGO lineage C.1.1.Ĭontinued genomic surveillance had led to the identification of more, new sequences in South Africa. However, it was later detected in Mozambique and at this point, had additional mutations (changes to the virus’s genetic code). Globally, C1 had a minimum transmission rate. The Delta variant, which was first identified in India in December 2020, quickly spread to more than 100 other countries and started to dominate Covid infections, including in South Africa. The variant is elevated from a VOI to a VOC when there is increased evidence of it fulfilling at least one of the above criteria.Ĭurrently, the Alpha, Beta, Gamma, and Delta variants are classified as VOCs.Įta, Iota, Kappa, and Lambda have been grouped under VOI. Most obese people know a lot about this often discussed problem and how diets are.The scientists will continue to monitor the spread of the variant, and are currently assessing whether it has increased transmissibility and may escape protection following vaccination through in vitro (laboratory) studies.Įmerging variants of the virus are classified as variants of interest (VOI) or variants of concern (VOC) by the World Health Organization (WHO).Īccording to the WHO, a VOI has undergone genetic changes that may allow it to be transmitted more easily cause more severe illness or reduce the effectiveness of vaccines or treatments, among other factors. Let us help you take back control of your life, today!ĭiets and obesity are aspects often mentioned together. Your first consultation will only take 15 minutes and is completely free, however this will be a life changing experience for you!

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